There are many benefits from taking CBD and Delta8/10. Both CBD and Delta products work hand in hand with the CB1 and CB2 receptors in the human body. The CB1 and CB2 receptors are responsible for muscle development, the nervous system, appetite and the immune system. There are also other benefits a person can reap from taking CBD or delta products.
1. Offset Anxiety and Depression
CBD’s ability to calm is perhaps its most popular effect and the reason its use is so widespread. A 2017 study in the Brazilian Journal of Psychiatry tested the anxiety levels of 57 men in a simulated public speaking test. Some received a placebo while others received either 150 milligrams, 300 milligrams or 600 milligrams of CBD before their speeches. Those who received 300 milligrams of CBD experienced significantly reduced anxiety during the test compared to those who received the placebo. Interestingly, participants who received either 150 or 600 milligrams of CBD experienced more anxiety during the test than the 300 milligrams group. Meanwhile, at least one study in mice revealed CBD had effects similar to the antidepressant imipramine. Human trials are needed, though, to confirm whether CBD can induce this same antidepressant reaction in our bodies.
2. Treat Select Epilepsy Syndromes
In some instances, CBD can be used to treat epileptic seizures. In 2018, the Food and Drug Administration (FDA) approved the use of CBD under the brand name Epidiolex to treat seizures resulting from Lennox-Gastaut syndrome and Dravet syndrome—two rare forms of epilepsy—in patients at least 2 years old. Three well-vetted studies provide the basis of support for the FDA’s decision. In these trials, 516 patients with Lennox-Gastaut syndrome or Dravet syndrome received either Epidiolex or a placebo. Epidiolex, when taken along with other prescribed medications, decreased the frequency of participants’ seizures compared to the placebo.
3. Reduce PTSD Symptoms
In a small 2018 study in the Journal of Alternative and Complementary Medicine, 11 people with post-traumatic stress disorder (PTSD) received CBD along with routine psychiatric care for eight weeks in an outpatient psychiatric clinic. Ten of the 11 experienced a decrease in their PTSD symptoms. CBD was generally well tolerated, the researchers write. Margaret Rajnic, a doctor of nursing practice experienced in medical cannabis and CBD, emphasizes the importance of using therapy in tandem with any type of cannabis or CBD for PTSD. “There is an amount of therapy that is needed for PTSD,” she says. “But CBD will give you that little bit of decreased anxiety.” Four other human trials from 2012 to 2016 suggest CBD reduces PTSD symptoms, although some include THC, or tetrahydrocannabinol, the main mind-altering element in cannabis. When THC and CBD work together, they create what’s called an “entourage effect,” complementing each other’s benefits and potency. For example, taking the same dose of THC and CBD together tempers the “high” from THC, while just a little THC paired with more CBD enhances the effects of the CBD.
4. Treat Opioid Addiction
Some studies—both preclinical animal and human clinical trials—suggest CBD could be used to help treat people who are dependent on opioids. In one such study, researchers administered CBD to people with heroin use disorder. Over the course of a week, CBD significantly reduced heroin users’ cue-induced cravings, withdrawal anxiety, resting heart rate and salivary cortisol levels. No serious adverse effects were found. Other studies find CBD helpful in reducing various psychiatric and medical symptoms like anxiety, insomnia and pain in patients with substance use disorders, indicating that CBD may be an effective treatment for opioid addiction. However, further studies are necessary.
5. Alleviate ALS Symptoms
Amyotrophic lateral sclerosis (ALS) is a disease that causes nerve cells in the brain and spinal cord to deteriorate, resulting in loss of muscle control that worsens over time. It’s not yet understood exactly why ALS occurs, although it can be hereditary in some cases. There’s no known cure, and there are only two FDA-approved medications to help treat ALS symptoms. Research suggests people with ALS can benefit from the entourage effect created by the combination of THC and CBD, similar to people with PTSD. In a 2019 study, patients received a combination of THC and CBD in varying doses depending on their needs and preferences. Those with mild, moderate or severe spasticity (muscle tightness and stiffness) due to ALS reported high levels of satisfaction with the treatment, and those with moderate to severe spasticity reported higher satisfaction rates than those with mild spasticity.
6. Relieve Unmanageable Pain
In 2005, Canada approved the use of Sativex, an oromucosal (absorbed in the lining of the mouth) spray with equal proportions of THC and CBD, for the treatment of multiple sclerosis-related central neuropathic pain. In 2007, Canada approved the medicine’s use again for cancer pain that proved unresponsive to other medications. Meanwhile, continued studies in the U.S. indicate CBD is effective in treating chronic, non-cancer pain. In one 2020 study, researchers administered CBD topically to a group of patients with symptomatic peripheral neuropathy (a result of brain nerve and spinal cord nerve damage) while another group with the same condition received a placebo. Results showed a significant reduction in intense, sharp pains and cold, itchy sensations in those who used the topical CBD compared to those who used the placebo. No participants reported adverse side effects. When introduced topically, CBD oil doesn’t affect the systemic issue as it might if it were introduced directly into the bloodstream. Instead, topical CBD is more localized and treats pain in a certain area. Since it’s more direct, it may have a more pronounced effect.
7. Ease Diabetic Complications
For starters, tests on human cells found that CBD helps reduce the effects of high glucose levels on other cells in the body, which typically precedes the development of diabetes and various complications. Researchers concluded that with further studies, CBD could have significant benefits when used in patients with diabetes, diabetic complications and plaque buildup in artery walls. In another small study, 13 patients with type 2 diabetes who weren’t on insulin treatment were given both CBD and a placebo (in lieu of insulin). Researchers found CBD decreased their levels of resistin (which causes resistance to insulin, the protein that regulates sugar levels) and increased their levels of glucose-dependent insulinotropic peptide (a hormone that ensures a sufficient release of insulin from digested food) compared to their baselines before they started the test. These results suggest CBD could be a natural treatment for diabetes by helping the body regulate insulin-related hormone levels.
8. Protect Against Neurological Disease
Preclinical and clinical studies show that CBD has antioxidant and anti-inflammatory properties. Researchers deduce these characteristics can provide significant neuroprotection, or protection against numerous pathological disorders. Several preclinical studies suggest CBD can produce beneficial effects against Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. Huntington’s disease and cerebral ischemia were also tested, although significant positive results were not recorded. Further clinical studies are needed to confirm CBD’s benefits when used as a treatment for these disorders.
9. Inhibit Arthritis Symptoms
Arthritis involves the deterioration of the tissues in and around your joints. There are several types of arthritis, and symptoms include pain, stiffness and loss of motion. Arthritis treatment usually targets pain relief and improved joint function. A 2006 study found that Sativex—a CBD-based botanical drug approved in the United Kingdom in 2010—promoted statistically significant improvements in quality of sleep, pain during movement and pain at rest in patients with rheumatoid arthritis when compared to a placebo. It was the first controlled trial of Sativex as a treatment for rheumatoid arthritis, involving 58 patients. CBD was found to have a pain-relieving effect, as well as an ability to suppress disease activity. In 2018, in a study of more localized treatment, researchers administered a synthetic CBD gel in either 250-milligram or 500-milligram doses daily or a placebo to patients with knee pain due to osteoarthritis. Patients also stopped taking any other anti-inflammatory medications or painkillers, with the exception of acetaminophen, before and during the study period. The results were interesting, although not entirely conclusive. On one hand, those treated with CBD did not experience much change in pain when compared with placebo patients. On the other hand, there were statistically significant differences between the group receiving the 250-milligram dose and the placebo group when measuring the average weekly improvement of their worst pain levels and their WOMAC (Western Ontario and McMaster Universities Arthritis Index) physical function rating. Additionally, men seemed to benefit from CBD more significantly than women in this test.
Delta 8 & Delta 10
1. Smoother Psychoactive Experience
Recreational cannabis users rarely use CBD because it doesn’t get them high. Some people, however, are very reactive to delta 9 THC from marijuana, meaning they easily get anxious at high doses.
If you’re the type that doesn’t enjoy the intense high that can make you experience anxiety and paranoia, delta 8 THC is a safer bet. Its potency has been measured at around 50–70% of the strength of delta 9 THC. Many delta 8 users claim the high from this cannabinoid is less edgy and allows them to remain focused and relaxed.
2. Appetite Boost
While delta 9 THC leads to stronger cognitive effects, delta 8 THC seems to be more effective at boosting appetite. Scientists believe that the appetite stimulation from delta 8 can be twice as strong as that induced by delta 9 THC.
If you like using cannabis for the munchies, then you’re going to have a great time with delta 8 THC, as a single dose can significantly increase your appetite.
These properties make delta 8 THC a potential aid for people struggling with low appetite and eating disorders.
One of the main reasons scientists have recently started to explore the benefits of delta 8 THC is how it acts on the brain.
Delta 8 THC has remarkable neuroprotective properties. It can inhibit the release of adenylyl cyclase and regulate potassium and calcium channels in the central nervous system. These actions can lead to better brain health.
Delta 8 can also increase the levels of choline and acetylcholine, which might prove helpful in the treatment of neurodegenerative disorders, such as Parkinson’s Disease and Alzheimer’s Disease.
Last but not least, delta 8 forms new neurons (neurogenesis), which results in improved cognitive functioning.
4. Better Sleep
Delta 8 THC induces a more mellow high than the one experienced by delta 9 users. The effects are very similar but less potent, including stress relief, euphoria, uplifting effects, and sedation. These effects are helpful for people who have insomnia.
5. Digestive Support
Delta 8 THC can be used to control nausea and vomiting. It can be as effective in doing so as delta 9 THC. The challenge that has prevented the wider use of delta 9 THC in treating nausea comes from its stronger psychoactive nature.
Delta 8 THC has similar antiemetic properties, but it has a lower anxiety and paranoia incidence. Researchers believe that delta 8 THC can be an effective adjunctive treatment for the side effects of conventional cancer therapies due to these effects.
The National Cancer Institute has found that delta 8 THC exerts anxiolytic effects. In simple words, it can help you ease stress and relax without exaggerating anxiety, as is the case with delta 9 THC in reactive users.
Delta 8 THC binds to the CB1 receptors in the brain; these receptors play a key role in modulating the psychoactive experience of cannabis. Delta 8 has a lesser affinity with CB1 receptors, hence its effectiveness at easing anxiety and stress.
Like CBD and other cannabinoids, delta 8 THC can ease muscle tension and help your body unwind. However, it doesn’t make you feel lethargic, so you can still do your daily duties while enjoying them to the fullest.
7. Pain Relief
Many people are choosing delta 8 THC over other cannabinoids for pain relief. According to the research performed on the topical application of delta 8 THC, it can relieve chronic pain. Chronic pain and inflammation are common in neuropathy, arthritis, Alzheimer’s disease, and multiple sclerosis.
The research on THC proves that it relieves chronic pain. THC offers anti-inflammatory properties and regulates the neurons and hormones that are engaged in pain transmission. When you take THC, your perception of pain changes.
Since delta 8 THC has similar properties to delta 9 THC — except for the intensity of the high — it’s within reason to assume that it, too, can make the pain more manageable.